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New Sister Study logo

Study Seeks North Carolina Women
Whose Sisters Had Breast Cancer

RESEARCH TRIANGLE PARK, N.C. - A new study looking at sisters of women with breast cancer has expanded its recruitment to include women living throughout North Carolina. The study, conducted by the National Institute of Environmental Health Sciences, part of the National Institutes of Health, is designed to determine the genetic and environmental causes of breast cancer.

The study will be expanded nationally in October, but currently includes statewide recruitment in Arizona, Florida, Illinois, Missouri, North Carolina, Ohio, Rhode Island, and Virginia.

[The Journal originally reported on this study in the April 2004 issue which featured Sara Williams, Sister Study Coordinator and also a breast cancer survivor.]

The study will eventually require 50,000 women volunteers nationwide, ages 35 to 74, including African American, Asian, Latina, and American Indian women, who have not had breast cancer but who have a sister who was diagnosed with breast cancer. Sisters of women with breast cancer are known to be at greater risk of the disease than other women. Dale Sandler, Ph.D., Chief of the Epidemiology Branch at NIEHS, said, "Volunteers will complete several questionnaires and provide a sample of their blood, urine, toenails, and household dust. With that, we will be able to look at the contributions of lifestyle, occupational and environmental exposures, and genes to breast cancer risk." The study, she added, will follow sisters for 10 years or more and compare those who develop breast cancer during that time to those who do not.

L to R: Sara Williams and sister, Denni Peebles

Volunteers in the Sister Study will help researchers identify factors that influence the development of breast cancer. "My sister Sara is a breast cancer survivor and advocate, but the national battle against this disease is far from over," said Denni Peebles of Winston-Salem, North Carolina. "Women are suffering every day as a result of breast cancer, and I am more than happy to participate in the Sister Study so that they can try to find the cause of this life-changing disease." (Peebles is pictured here, right, with her sister Sara Williams, left. Williams has served as Recruitment Coordinator for the Sister Study since 2001.)

To volunteer or learn more about the Sister Study, go to the web site www.sisterstudy.org or call toll free 1-877-4SISTER (877-474-7837).


Sara Williams M.A.
NIEHS Contractor
Research Associate
CODA, Inc.
1009 Slater Road, Suite 120
Durham NC 27703
phone: 919.941.9344 X 343
fax: 919.941.9349
willia50@niehs.nih.gov